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Article Reprints | Primers | Posters | Resources | Seminars and Presentations
Software | Tools | Bibliography

Article Reprints

• AR-8647A: Analytical Ultracentrifugation as a contemporary Biomolecular Research Tool
• AR-9663A: Characterizing the Aggregation and Conformation of Protein Therapeutics
• AR-9925A: Sedimentation for Success: Characterizing Small-Molecule/Protein Interactions by Sedimenation Analysis Helps Validate Lead Series Early in the Drug Discovery Process
• AR-10229A: Applying Selective Biophysical Techniques in Assessing the Comparability of Protein Therapeutics--Case Studies. Yijia Jiang, PhD and Linda Owens Narhi, PhD, Amgen, Inc. American Pharmaceutical Review, Jul./Aug. 2006

Primers

• Introduction to Analytical Ultracentrifugation
• Self-Associating Systems in the Analytical Ultracentrifuge

Posters

• P-10119B: ProteomeLab XL-A/XL-I Protein Characterization System -- Native Condition Protein Characterization

Resources

• XL-A/XL-I Links
• XL-A/XL-I Customer Training Course
• Sedimentation Equilibrium
• Sedimentation Velocity

Seminars and Presentations 

• Quantifying Protein Aggregates by Sedimentation Velocity, by Michael Stoner, Ph.D.
  • View the Webinar
  • Order the CD-ROM
• Sedimentation for Success: Characterizing Small-Molecule/ Protein Interactions by Sedimentation Equilibrium, by Michelle Arkin, Ph.D.
  • View the Webinar
  • Order the CD-ROM
• Use of the Analytical Ultracentrifuge to Characterize Very Large Complex Biopharmaceuticals (Viral Gene Therapy Delivery Systems), by Steven Berkowitz, Ph.D.
  • View the Webinar
  • Order the CD-ROM
• View the Video Clips: AUC in Drug Discovery and Characterization, an interview with Preston Hensley and Tom Laue.
  • Introductions (wmv file, 25 sec)
  • What is driving AUC interest in biopharma? (wmv file, 1:13 min)
  • Which instruments and techniques are commonly used in therapeutic drug characterization? (wmv file, 1:27 min)
  • Where does AUC have a role in the development process of new drugs? (wmv file, 28 sec)

Software

• XL-A/XL-I Data Analysis Software
• Additional Data Analysis Software Available on the Internet

Tools

• Rotor Speed Selection Charts for Beckman Coulter centrifugation products
• Cell Assembly Diagram for the An-50 Ti and An-60 Ti rotors

Bibliography

• XL-A/XL-I Bibliography Search
   

• Go to Protein Characterization Page

• Go to ProteomeLab Home Page

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