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T3 Update Online -- Tips, Tricks and Techniques for Users of Beckman Coulter Life Science Automation |
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Welcome From the Editors -- Issue 1, July 2007
Welcome to the Summer 2007 Issue of T3 Update Online. We have spent the past year busily preparing new products that span the continuum among academic research, drug discovery and genetic analysis.
In this issue, we introduce you to some of these technologies. This issue features an outstanding new chemistry, the GenFind™ V2 Purification System, from our Agencourt® team, and our innovative PARADIGM™ Detection Platform. Plus the BioRAPTR FRD™ and PicoRAPTR™ Microfluidic Workstations are featured below in our "New Hardware" section.
As always, posters and other scientific material form the backbone of the issue. We’ve introduced a new feature called "Club Biomek Forum," an online resource that is full of interesting information submitted by you, our users.
We're glad to bring you, what we hope you will agree is, the best T3 Update Online ever!

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Marc Goldstein, Ph.D., Mary X. Guan and Keith Roby. Learn more in the "About the Editors" section.

Download a printable version of the T3 Update On-Line (PDF Format, 1.19 MB). |
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New Chemistry |
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Agencourt® Genfind™ V2 Purification System
The Agencourt Genfind v2 DNA purification system isolates and purifies genomic DNA (gDNA) from whole blood, serum and FTA cards. The kit is powered by cutting-edge Solid Phase Reversible Immobilization (SPRI®) paramagnetic bead-based technology to effectively produce high yields of quality DNA for downstream applications such as PCR and genotyping. The method can be run in manual or automated formats using Beckman Coulter's Biomek® NXP or FXP automated workstations. more
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New Hardware |
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New Industrial Robotics Solutions
"Simplify, Automate and Innovate." That is the recipe for an Industrial Robotics Solution from Beckman Coulter. Incorporating Beckman Coulter's standard hardware and third-party devices, and centered around a Motoman* fixed-base or rail-based arm, these complete systems demonstrate the power of Beckman Coulter in providing complete process automation.
Want to learn more? Click here for the (PDF) brochure. |
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New Modular Detection Platform PARADIGM™ Certified for HTRF*
Beckman Coulter's PARADIGM Detection Platform has been certified for HTRF in combination with Cisbio assays and reagents. PARADIGM features a selection of detection cartridges that can be interchanged in less than five minutes to meet different assay needs, making this the first user-upgradeable and user-configurable multimode reader. more |
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BioRAPTR FRD™ and PicoRAPTR™ Microfluidic Workstations for High-Throughput Assay Miniaturization
With the addition of the new BioRAPTR FRD and PicoRAPTR Microfluidic workstations, Beckman Coulter's automation capabilities span the complete range of volumes, from tubes to microplates to high density 1536-well and 3456-well ChemLib™ plates. more |
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ChemLib™ 1536-Well and 3456-Well Microplates
Beckman Coulter now provides ChemLib 1536-well and 3456-well microplates supported on the BioRAPTR FRD and PicoRAPTR workstations. ChemLib 1536-well microplates are also supported on the Biomek NXP and FXP platforms using the 384-multichannel. Superior material properties and intelligent design provide advantages to life science research miniaturization. more |
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More News |
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New Collaboration - Agencourt, Affymetrix Clinical Services Lab and NuGEN Technologies
Agencourt Bioscience, Affymetrix Clinical Services Laboratory (ACSL) and NuGEN Technologies, Inc. have announced a collaboration that has yielded a service offering for the automated isolation and target preparation of RNA from whole blood samples collected, stabilized and stored in PAXgene Blood Tubes*. more |
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New Beckman Coulter Online Catalog
Beckman Coulter launched its new online catalog in June 2007. The new electronic catalog (eCatalog) enables users to browse products and purchase most reagents, consumables and some products online with the new eStore feature.
Click link for Research Automation Page in the eCatalog. |

Genomics
Target Preparations
- Poster: Zhu Zhu, Dan Allison, Yu Suen, Handy Yowanto, Tim Lancaster, Jeremy Smith and Keith Roby: Target Preparation for GeneChip Expression Analysis Using the Biomek® 3000 Laboratory Automation Workstation and ArrayPlex Application. more

- Poster: Handy Yowanto, Don Misumi, Joe Don Heath, William Biggs and Cynthia French: Automated NuGEN Ovation* Whole Blood Solution for Blood Expression Profiling on the Biomek FX Laboratory Automation Workstation. more

Sample Preparations
- Poster: Matthew Cu and Amy Yoder: Using the Biomek 3000 Laboratory Automation Workstation and Agencourt® RNAdvance™ Cell Kit to Isolate and Perform Quantitation and Normalization on Total RNA from Cultured Eukaryotic Cells. more


Automation
Assay Miniaturization
- Poster: Sébastien Guiral, Frédéric Masse, Jeffrey Karg, Doug Kroncke and Christine Brideau: Nanoliter Dispensing of Compounds into Assay Plates Using Disposable PocketTips*. more

- Poster: Carolyn Klecker, Patricia Gill, Derek Hook, Doug Kroncke: A Case Study Examining Microliter vs Nanoliter Transfers in a FRET Assay. more


Drug Discoveries
ADMETox
- Poster: Yu Suen and Konstantin Tsinman: Automation of Double-Sink PAMPA* Permeability and μSOL Solubility Assays on the Biomek FX ADMETox Assay Workstation. more
- Poster: Yu Suen and Keith Roby: Automation of the FlowCytomix Multiplex Human Th1/Th2 10Plex Assay on the Biomek FX Laboratory Automation Workstation. more


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Poster: Rudolf Lucas, Christoph Wiesner, Maren Pflueger, Barbara Entler, Rainer Fedra, Richard Oseghale, Lore Koller, Josef Atzler, Wolfgang Schütt, Christoph Kleber and Harald Hundsberger: A Novel High-Throughput Cell-Based ELISA Assay for Screening of Anti-Inflammatory Drugs. more
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Poster: Christoph Wiesner, Rudolf Lucas, Maren Pflueger, Christian Knoll, Wolfgang Schütt, Jim Barry, Josef Atzler and Harald Hundsberger: Simultaneous Screening for Apoptosis Versus Necrosis by Means of Dual Emission Read-Out Using Multimode Detection.
more

* All trademarks are the property of their respective owners. Where applicable,
the PCR process is covered by patents owned by Roche Molecular Systems, Inc.,
and F. Hoffmann-LaRoche, Ltd.
For comments or questions about T3 Update, please contact the T3
Editor.
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