eLabNotebook > Genomic Analysis > DNA Sizing on the CEQ™


Beckman Coulter Concept Application (system support)

Highly Precise DNA Sizing on the CEQ™ 2000 Fragment Analysis System

Keith Roby, Mark Dobbs, Doni Clark, Scott Boyer, and Graham Threadgill
Beckman Coulter, Inc.

Capillary electrophoresis is rapidly supplanting conventional slab gel electrophoresis in moderate-to- high–throughput laboratories that desire automated separations with a simple user interface. Our data demonstrates that the CEQ 2000 DNA Analysis System from Beckman Coulter precisely sized microsatellite amplification products in the size range of 200, 300, and 400, to a standard deviation of ≤ 0.27 bases, regardless of which capillary within an array, run, gel lot, or instrument was used to separate the sample. This level of accuracy means that from experiment to experiment, accurate and reliable data will be generated.

* All trademarks are the property of their respective owners. Where applicable, the PCR process is covered by patents owned by Roche Molecular Systems, Inc., and F. Hoffman-LaRoche, Ltd.

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